Package: vaccine
Type: Package
Title: Statistical Tools for Immune Correlates Analysis of Vaccine
        Clinical Trial Data
Version: 1.4.0
Authors@R: person("Avi", "Kenny", email = "avi.kenny@gmail.com", role = c("aut", "cre"))
Description: Various semiparametric and nonparametric statistical tools
        for immune correlates analysis of vaccine clinical trial data.
        This includes calculation of summary statistics and estimation
        of risk, vaccine efficacy, controlled effects (controlled risk
        and controlled vaccine efficacy), and mediation effects
        (natural direct effect, natural indirect effect, proportion
        mediated). See Gilbert P, Fong Y, Kenny A, and Carone, M (2022)
        <doi:10.1093/biostatistics/kxac024> and Fay MP and Follmann DA
        (2023) <doi:10.48550/arXiv.2208.06465>.
License: GPL-3
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.3.2
VignetteBuilder: knitr
Imports: dplyr (>= 1.0.10), fdrtool (>= 1.2.17), ggplot2 (>= 3.4.0),
        ggpubr (>= 0.5.0), methods (>= 4.2.2), rlang (>= 1.0.6), Rsolnp
        (>= 1.16), splines (>= 4.2.2), stats (>= 4.2.2), SuperLearner
        (>= 2.0.28), survival (>= 3.4.0), survML (>= 0.0.0.9000),
        truncnorm (>= 1.0.8), e1071 (>= 1.7.12), gam (>= 1.22.3),
        ranger (>= 0.14.0), utils (>= 4.3.2), MASS (>= 7.3.61)
Suggests: knitr, rmarkdown, testthat (>= 3.0.0)
Depends: R (>= 2.10)
Config/testthat/edition: 3
URL: https://avi-kenny.github.io/vaccine/
BugReports: https://github.com/Avi-Kenny/vaccine/issues
Config/pak/sysreqs: cmake make libgsl0-dev libicu-dev
Repository: https://avi-kenny.r-universe.dev
Date/Publication: 2026-09-29 12:45:59 UTC
RemoteUrl: https://github.com/avi-kenny/vaccine
RemoteRef: HEAD
RemoteSha: 15de36a903654dcdf992237ed5cc7e145f4eed0c
NeedsCompilation: no
Packaged: 2026-09-29 16:56:55 UTC; root
Author: Avi Kenny [aut, cre]
Maintainer: Avi Kenny <avi.kenny@gmail.com>