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SimEngine - A Modular Framework for Statistical Simulations in R

An open-source R package for structuring, maintaining, running, and debugging statistical simulations on both local and cluster-based computing environments.See full documentation at <https://avi-kenny.github.io/SimEngine/>.

Last updated

6.22 score 12 stars 55 scripts 198 downloads

vaccine - Statistical Tools for Immune Correlates Analysis of Vaccine Clinical Trial Data

Various semiparametric and nonparametric statistical tools for immune correlates analysis of vaccine clinical trial data. This includes calculation of summary statistics and estimation of risk, vaccine efficacy, controlled effects (controlled risk and controlled vaccine efficacy), and mediation effects (natural direct effect, natural indirect effect, proportion mediated). See Gilbert P, Fong Y, Kenny A, and Carone, M (2022) <doi:10.1093/biostatistics/kxac024> and Fay MP and Follmann DA (2023) <doi:10.48550/arXiv.2208.06465>.

Last updated

5.42 score 4 stars 22 scripts 540 downloads

steppedwedge - Analyze Data from Stepped Wedge Cluster Randomized Trials

Provide various functions and tools to help fit models for estimating treatment effects in stepped wedge cluster randomized trials. Implements methods described in Kenny, Voldal, Xia, and Heagerty (2022) "Analysis of stepped wedge cluster randomized trials in the presence of a time-varying treatment effect", <doi:10.1002/sim.9511>.

Last updated

5.38 score 3 stars 2 scripts 202 downloads